Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 16/20 | 0.37 |
| ▸ | ATR | Q13535 | 15/20 | 0.37 |
| ▸ | ATRIP | Q8WXE1 | 15/20 | 0.37 |
| ▸ | ATM | Q13315 | 10/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.36 |
| ▸ | MTOR | P42345 | 8/20 | 0.35 |
| ▸ | SERPINA2 | P20848 | 6/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27124019 | 1.00 | PRKDC (0.37) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541715 | 1.00 | PRKDC (0.37) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541852 | 0.91 | PRKDC (0.39) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL30359398 | 0.91 | PRKDC (0.39) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541913 | 0.91 | PRKDC (0.38) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL30359433 | 0.91 | PRKDC (0.38) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541719 | 0.91 | PRKDC (0.38) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL30359438 | 0.91 | PRKDC (0.38) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541836 | 0.88 | S1PR1 (0.33) | MTORWDR5 | |
| SCHEMBL29559929 | 0.88 | S1PR1 (0.33) | MTORWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |