Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 18/20 | 0.45 |
| ▸ | ATR | Q13535 | 15/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 15/20 | 0.45 |
| ▸ | ATM | Q13315 | 10/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 15/20 | 0.44 |
| ▸ | MTOR | P42345 | 6/20 | 0.42 |
| ▸ | SERPINA2 | P20848 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541775 | 1.00 | PRKDC (0.45) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541839 | 0.88 | PRKDC (0.45) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541726 | 0.84 | SLC16A3 (0.39) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL21541900 | 0.84 | PRKDC (0.65) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL30359440 | 0.84 | PRKDC (0.65) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541809 | 0.80 | PRKDC (0.42) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL30359523 | 0.76 | SMG1 (0.38) | MTOR | |
| SCHEMBL30359500 | 0.76 | PRKDC (0.62) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541771 | 0.76 | PRKDC (0.62) | PRKDCATRATRIPATMPIK3CB | |
| SCHEMBL21541748 | 0.75 | ATM (0.56) | PRKDCATRATRIPATMPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |