Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 20/20 | 0.82 |
| ▸ | PIK3CB | P42338 | 17/20 | 0.82 |
| ▸ | ATR | Q13535 | 16/20 | 0.82 |
| ▸ | ATRIP | Q8WXE1 | 16/20 | 0.82 |
| ▸ | ATM | Q13315 | 10/20 | 0.82 |
| ▸ | MTOR | P42345 | 6/20 | 0.74 |
| ▸ | SERPINA2 | P20848 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541782 | 1.00 | PRKDC (0.82) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541902 | 0.86 | PRKDC (0.66) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL30359525 | 0.84 | PRKDC (0.68) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL30359511 | 0.84 | PRKDC (0.68) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541790 | 0.84 | PRKDC (0.68) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541818 | 0.84 | PRKDC (0.68) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL20374457 | 0.83 | PRKDC (0.67) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541725 | 0.82 | PRKDC (0.69) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL21541737 | 0.82 | PRKDC (0.66) | PRKDCPIK3CBATRATRIPATM | |
| SCHEMBL30359510 | 0.82 | PRKDC (0.69) | PRKDCPIK3CBATRATRIPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |