Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 16/20 | 0.62 |
| ▸ | ATM | Q13315 | 12/20 | 0.62 |
| ▸ | ATR | Q13535 | 14/20 | 0.45 |
| ▸ | ATRIP | Q8WXE1 | 13/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.45 |
| ▸ | MTOR | P42345 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541854 | 1.00 | PRKDC (0.62) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541835 | 0.87 | PRKDC (0.61) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541783 | 0.87 | PRKDC (0.61) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541740 | 0.85 | PRKDC (0.68) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL29559426 | 0.85 | PRKDC (0.59) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541751 | 0.85 | PRKDC (0.59) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL30359521 | 0.85 | PRKDC (0.81) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541879 | 0.85 | PRKDC (0.81) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL20374454 | 0.84 | PRKDC (0.73) | PRKDCATMATRATRIPPIK3CB | |
| SCHEMBL21541764 | 0.82 | ATM (0.43) | PRKDCATMATRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567041-B1 | SUBSTITUTED FUSED HETEROARYL COMPOUND SERVING AS A KINASE INHIBITOR, AND APPLICATIONS THEREOF | IMPACT THERAPEUTICS SHANGHAI INC (CN) | 2023-12-27 | — | — | EP | claimed |
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |