Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 15/20 | 0.82 |
| ▸ | ATM | Q13315 | 15/20 | 0.82 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.49 |
| ▸ | ATR | Q13535 | 12/20 | 0.49 |
| ▸ | ATRIP | Q8WXE1 | 10/20 | 0.49 |
| ▸ | MTOR | P42345 | 8/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374540 | 1.00 | PRKDC (0.82) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL20374463 | 0.90 | PRKDC (1.00) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL30359505 | 0.90 | PRKDC (1.00) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL21541753 | 0.90 | PRKDC (0.67) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL21541872 | 0.82 | PRKDC (0.81) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL21541855 | 0.80 | PRKDC (0.82) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL21541879 | 0.79 | PRKDC (0.81) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL30359521 | 0.79 | PRKDC (0.81) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL21541772 | 0.79 | PRKDC (0.77) | PRKDCATMPIK3CBATRATRIP | |
| SCHEMBL23093866 | 0.77 | ATM (0.76) | PRKDCATMPIK3CBATRATRIP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |