Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 19/20 | 0.61 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.61 |
| ▸ | MTOR | P42345 | 15/20 | 0.61 |
| ▸ | PRKDC | P78527 | 4/20 | 0.61 |
| ▸ | ATR | Q13535 | 3/20 | 0.61 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.61 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.61 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21541811 | 1.00 | ATM (0.61) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL21541844 | 0.88 | ATM (0.51) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL22891694 | 0.83 | ATM (0.62) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL30011731 | 0.83 | ATM (0.62) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL21541745 | 0.83 | ATM (0.55) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL30359524 | 0.83 | ATM (0.55) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL24381740 | 0.82 | ATM (0.68) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL30012304 | 0.82 | ATM (0.62) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL30013029 | 0.81 | ATM (0.59) | ATMPIK3CAMTORPRKDCATR | |
| SCHEMBL17241361 | 0.78 | ATM (0.59) | ATMPIK3CAMTORPRKDCATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167941-B | Substituted fused heteroaryl compounds as kinase inhibitors and uses thereof | 上海瑛派药业有限公司 | 2023-04-04 | — | — | CN | disclosed |