SCHEMBL30360261

SCHEMBL30360261

CC(C)(C)c1nccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.64
TSHR P16473 2/20 0.64
CYP2C19 P33261 1/20 0.64
CFTR P13569 1/20 0.58
GOPC Q9HD26 1/20 0.58
CYP2A6 P11509 2/20 0.55
PLAU P00749 2/20 0.50
F12 P00748 1/20 0.50
NCF1 P14598 1/20 0.50
NOS3 P29474 1/20 0.50
NOS1 P29475 1/20 0.50
NOS2 P35228 1/20 0.50
BACE1 P56817 1/20 0.50
SSTR1 P30872 1/20 0.46
SSTR4 P31391 1/20 0.46
HRH4 Q9H3N8 1/20 0.42
PLG P00747 1/20 0.42
GRM4 Q14833 1/20 0.41
LMNA P02545 3/20 0.41
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30360262 1.00 CYP3A4 (0.64) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL762186 1.00 CYP3A4 (0.64) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL26097343 0.86 CYP3A4 (0.62) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL28223755 0.84 CYP3A4 (0.70) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL26509260 0.84 CYP3A4 (0.60) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL30018408 0.84 CYP3A4 (0.60) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL4379626 0.84 CYP3A4 (0.60) CYP3A4TSHRCYP2C19CFTRGOPC
Hydrochloric Acid SCHEMBL30017443 0.82 CYP3A4 (0.58) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL19659677 0.81 CYP3A4 (0.61) CYP3A4TSHRCYP2C19CFTRGOPC
SCHEMBL3294907 0.79 CFTR (0.58) CYP3A4TSHRCYP2C19CFTRGOPC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110229192-B Deuterated iridium complex and preparation method and application thereof 南京佳诺霖光电科技有限公司 2023-04-18 CN claimed