SCHEMBL30360522

SCHEMBL30360522

c1ccc2c(-c3ccc(N(c4ccc(-c5nc6ccccc6o5)cc4)c4ccc(-c5nc6ccccc6o5)cc4)cc3)cccc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.51
RAB9A P51151 4/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
ATM Q13315 1/20 0.51
ALDH1A1 P00352 6/20 0.51
HPGD P15428 5/20 0.51
HSD17B10 Q99714 5/20 0.51
KDM4E B2RXH2 4/20 0.51
TP53 P04637 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MAPT P10636 5/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
MMP2 P08253 1/20 0.46
MMP9 P14780 1/20 0.46
MMP8 P22894 1/20 0.46
MMP13 P45452 1/20 0.46
PTGS2 P35354 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22578633 1.00 NPC1 (0.51) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13426666 0.97 NPC1 (0.49) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13133823 0.97 NPC1 (0.49) NPC1RAB9AMEN1KMT2AATM
SCHEMBL14330718 0.97 NPC1 (0.49) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13426648 0.96 NPC1 (0.48) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13426656 0.95 HPGD (0.47) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13426670 0.94 HPGD (0.46) NPC1RAB9AMEN1KMT2AATM
SCHEMBL24686648 0.92 NPC1 (0.44) NPC1RAB9AMEN1KMT2AATM
SCHEMBL28681367 0.92 NPC1 (0.59) NPC1RAB9AMEN1KMT2AATM
SCHEMBL22578583 0.92 TP53 (0.47) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240260457-A1 ORGANIC EL DEVICE, AMINE COMPOUND HAVING BENZAZOLE RING STRUCTURE, AND METHOD IN WHICH SAID AMINE COMPOUND IS USED IN CAPPING LAYER OF ORGANIC EL DEVICE HODOGAYA CHEMICAL CO., LTD. (JP) 2024-08-01 US disclosed
US-11997870-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2024-05-28 US disclosed
US-11974499-B2 Organic EL device, amine compound having benzazole ring structure, and method in which said amine compound is used in capping layer of organic EL device HODOGAYA CHEMICAL CO., LTD. (JP) 2024-04-30 US disclosed
EP-4207947-B1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO LTD (JP) 2024-03-13 EP disclosed
US-20230309339-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2023-09-28 US disclosed
US-11706943-B2 Organic electroluminescent element and method for producing same HODOGAYA CHEMICAL CO., LTD. (JP) 2023-07-18 US disclosed
EP-4207947-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING SAME Hodogaya Chemical Co., Ltd. (JP) 2023-07-05 EP disclosed
CN-111567141-B Organic EL element, amine compound having benzoxazole ring structure, and method for using same in capping layer of organic EL element 保土谷化学工业株式会社 2023-06-13 CN disclosed
EP-3731599-B1 ORGANIC ELECTROLUMINESCENCE ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2023-05-03 EP disclosed