Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 6/20 | 0.43 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26516668 | 1.00 | HRH3 (0.45) | HRH3HTR6MAP4K1PIK3CAPRKDC | |
| SCHEMBL26516735 | 0.89 | HRH3 (0.41) | HRH3HTR6MAP4K1PIK3CAPRKDC | |
| SCHEMBL30360625 | 0.89 | HRH3 (0.41) | HRH3HTR6MAP4K1PIK3CAPRKDC | |
| SCHEMBL26516667 | 0.82 | MAP4K1 (0.39) | MAP4K1PIK3CAPRKDCRAD52LRRK2 | |
| SCHEMBL26516681 | 0.81 | MAP4K1 (0.41) | MAP4K1RAD52LRRK2GPR119ACVR1 | |
| SCHEMBL29006623 | 0.81 | MAP4K1 (0.41) | MAP4K1RAD52LRRK2GPR119ACVR1 | |
| SCHEMBL26516674 | 0.81 | MAP4K1 (0.41) | MAP4K1RAD52LRRK2GPR119ACVR1 | |
| SCHEMBL30360601 | 0.80 | MAP4K1 (0.47) | HRH3MAP4K1PIK3CARAD52LRRK2 | |
| SCHEMBL26516557 | 0.80 | MAP4K1 (0.47) | HRH3MAP4K1PIK3CARAD52LRRK2 | |
| SCHEMBL30360598 | 0.80 | MAP4K1 (0.48) | MAP4K1RAD52ACVR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200015-A1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | Bristol-Myers Squibb Company (US) | 2023-06-28 | — | — | EP | claimed |
| CN-115956077-A | Substituted heteroaryl compounds as TLR9 inhibitors | 百时美施贵宝公司 | 2023-04-11 | — | — | CN | claimed |