SCHEMBL30360689

SCHEMBL30360689

OCCc1cc2c(cc1Br)OCO2

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.48
CYP2D6 P10635 3/20 0.48
CYP1A2 P05177 2/20 0.48
CYP2C19 P33261 2/20 0.48
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HSP90AA1 P07900 3/20 0.36
HSP90B1 P14625 3/20 0.36
TRAP1 Q12931 3/20 0.36
ALDH1A1 P00352 1/20 0.36
HPGD P15428 1/20 0.36
CYP2C9 P11712 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
PKM P14618 1/20 0.35
POLB P06746 1/20 0.35
DPP4 P27487 1/20 0.34
KCNH2 Q12809 1/20 0.34
DPP8 Q6V1X1 1/20 0.34
DPP9 Q86TI2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17980277 1.00 CYP3A4 (0.48) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL19812792 0.90 MEN1 (0.43) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL30360652 0.90 MEN1 (0.43) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL281746 0.83 CYP3A4 (0.46) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL29961170 0.83 CYP3A4 (0.46) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL28346620 0.77 TAAR1 (0.44) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL1520657 0.77 CYP3A4 (0.44) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL19812759 0.77 PRKCI (0.36) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL30360658 0.77 PRKCI (0.36) CYP3A4CYP2D6CYP1A2CYP2C19MEN1
SCHEMBL9150522 0.76 CYP3A4 (0.41) CYP3A4CYP2D6CYP1A2CYP2C19MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116514761-A Compounds, compositions and uses thereof 赛诺维信制药公司 2023-08-01 CN disclosed
CN-116283877-A Compounds, compositions and uses thereof 赛诺维信制药公司 2023-06-23 CN disclosed
CN-110088107-B Compounds, compositions and uses thereof 赛诺维信制药公司 2023-04-14 CN disclosed