SCHEMBL30360795

SCHEMBL30360795

COc1cc(F)c2nc(-c3cc(C)cc4c(=O)n(C(C)C)cnc34)sc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 5/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28894705 1.00 F2RL3 (0.78) F2RL3
SCHEMBL28428005 0.89 F2RL3 (0.78) F2RL3
SCHEMBL30360784 0.89 F2RL3 (0.78) F2RL3
SCHEMBL30360791 0.87 F2RL3 (1.00) F2RL3
SCHEMBL28435784 0.87 F2RL3 (1.00) F2RL3
SCHEMBL28438209 0.85 F2RL3 (0.78) F2RL3
SCHEMBL30360796 0.85 F2RL3 (0.78) F2RL3
SCHEMBL30360786 0.83 F2RL3 (0.75) F2RL3
SCHEMBL28428127 0.83 F2RL3 (0.75) F2RL3
SCHEMBL30360797 0.81 F2RL3 (0.74) F2RL3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111440161-B Bicyclic heteroaryl compound with PAR4 antagonistic activity and application thereof 中国药科大学 2023-04-14 CN disclosed