Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 18/20 | 1.00 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | EIF2AK2 | P19525 | 2/20 | 0.48 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL869204 | 1.00 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL869562 | 0.87 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK1 | |
| SCHEMBL869310 | 0.85 | EIF2AK3 (0.75) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL868645 | 0.85 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2 | |
| SCHEMBL869091 | 0.85 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL869888 | 0.85 | EIF2AK3 (0.74) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL868994 | 0.84 | EIF2AK3 (0.73) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL868836 | 0.84 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK1 | |
| SCHEMBL869218 | 0.83 | EIF2AK3 (0.72) | EIF2AK3RIPK1EIF2AK2EIF2AK1 | |
| SCHEMBL868634 | 0.83 | EIF2AK3 (1.00) | EIF2AK3RIPK1EIF2AK2EIF2AK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137667-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF CORONAVIRUS INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-04 | — | — | US | claimed |
| US-20230137667-A1 | METHODS AND COMPOSITIONS FOR TREATMENT OF CORONAVIRUS INFECTION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-04 | — | — | US | disclosed |