Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15312100 | 1.00 | ESR1 (0.47) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL18898167 | 1.00 | ESR1 (0.47) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL10074007 | 1.00 | ESR1 (0.47) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL2719199 | 1.00 | ESR1 (0.47) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL19655436 | 0.91 | ESR1 (0.47) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL28193660 | 0.89 | CYP3A4 (0.51) | ESR1ESR2CYP3A4TTRALOX15B | |
| SCHEMBL26946067 | 0.88 | ESR1 (0.44) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL30362809 | 0.88 | ESR1 (0.45) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL2716865 | 0.88 | ESR1 (0.45) | ESR1ESR2CYP3A4MAOAMAOB | |
| SCHEMBL10098028 | 0.88 | ESR1 (0.45) | ESR1ESR2CYP3A4MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116139125-A | Combination therapy | 梅制药公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-116113414-A | Combination therapy | 梅制药公司 | 2023-05-12 | — | — | CN | disclosed |
| EP-4164632-A1 | COMBINATION THERAPIES | MEI Pharma, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-107427003-B | Combination therapy | 梅制药公司 | 2023-01-31 | — | — | CN | disclosed |