Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28461381 | 1.00 | KMT2A (0.71) | KMT2ATP53CYP3A4MEN1BLM | |
| SCHEMBL10957358 | 0.88 | MEN1 (0.68) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL10953582 | 0.85 | TP53 (0.77) | KMT2ATP53CYP3A4MEN1BLM | |
| SCHEMBL10953960 | 0.85 | KMT2A (0.77) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL10956224 | 0.84 | TP53 (0.76) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL10451458 | 0.84 | TP53 (0.76) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL29439935 | 0.83 | KMT2A (1.00) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL635010 | 0.83 | KMT2A (1.00) | KMT2ATP53CYP3A4MEN1BLM | |
| Furegrelate SCHEMBL30530940 | 0.82 | KMT2A (0.98) | KMT2ATP53CYP3A4MEN1BLM | |
| SCHEMBL5398383 | 0.81 | PIM1 (0.73) | KMT2ATP53CYP3A4MEN1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111646889-B | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2023-01-31 | — | — | CN | claimed |
| CN-111646889-B | Green synthesis method of drug active molecules GC-24 and furaldehyde | 兰州大学 | 2023-01-31 | — | — | CN | disclosed |