Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD38 | P28907 | 14/20 | 0.49 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KHK | P50053 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25135722 | 1.00 | CD38 (0.49) | CD38SMYD3LRRK2CYP2D6CYP2B6 | |
| Hydrochloric Acid SCHEMBL30363726 | 0.99 | CD38 (0.48) | CD38SMYD3LRRK2CYP2D6CYP2B6 | |
| SCHEMBL30364004 | 0.93 | CD38 (0.53) | CD38SMYD3LRRK2CYP2D6CYP2B6 | |
| SCHEMBL25135717 | 0.93 | CD38 (0.53) | CD38SMYD3LRRK2CYP2D6CYP2B6 | |
| Hydrochloric Acid SCHEMBL30363855 | 0.92 | CD38 (0.52) | CD38SMYD3LRRK2CYP2D6CYP2B6 | |
| SCHEMBL25135704 | 0.88 | LRRK2 (0.47) | CD38LRRK2CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135727 | 0.88 | CD38 (0.61) | CD38LRRK2CYP2D6CYP2B6CYP2C19 | |
| Hydrochloric Acid SCHEMBL30363932 | 0.87 | LRRK2 (0.46) | CD38LRRK2CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL25135686 | 0.87 | CD38 (0.48) | CD38LRRK2 | |
| SCHEMBL25135666 | 0.87 | CD38 (0.48) | CD38LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | CD38 1/4885SMYD3 2117/4885LRRK2 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.