SCHEMBL30365518

SCHEMBL30365518

Cc1cccc(-c2nc(-c3ccc4ccccc4c3F)[nH]c2-c2ccncc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 20/20 1.00
CSNK1D P48730 9/20 1.00
CSNK1E P49674 9/20 1.00
MAPK13 O15264 2/20 0.58
MAPK12 P53778 2/20 0.58
MAPK11 Q15759 2/20 0.58
GCGR P47871 1/20 0.58
RAF1 P04049 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17002323 1.00 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL17002312 0.85 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL30365700 0.85 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL26677066 0.85 MAPK14 (0.73) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL29465653 0.83 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL17002321 0.83 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL17002322 0.83 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL17002320 0.80 MAPK14 (1.00) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL22778283 0.80 MAPK14 (0.72) MAPK14CSNK1DCSNK1EMAPK13MAPK12
SCHEMBL17002235 0.79 MAPK14 (1.00) MAPK14CSNK1DCSNK1E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109890805-B Substituted azole derivatives for the production, proliferation and differentiation of hematopoietic stem and progenitor cells 新加坡国立大学 2023-04-04 CN disclosed