Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.60 |
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358366 | 1.00 | PIK3CA (0.60) | PIK3CACDK1YTHDC1NT5ESMN1; SMN2 | |
| SCHEMBL13828421 | 0.85 | ADORA1 (0.56) | PIK3CACDK1YTHDC1SMN1; SMN2ADORA1 | |
| SCHEMBL7299820 | 0.83 | CDK1 (0.51) | PIK3CACDK1YTHDC1ADORA1TLR7 | |
| SCHEMBL13828322 | 0.83 | PIK3CA (0.60) | PIK3CAHDAC1MTORADORA1TLR7 | |
| SCHEMBL13828332 | 0.83 | PIK3CA (0.71) | PIK3CACDK1HDAC1MTORADORA1 | |
| SCHEMBL24955551 | 0.83 | PIK3CA (0.60) | PIK3CACDK1HDAC1MTORADORA1 | |
| SCHEMBL13828313 | 0.83 | PIK3CA (0.60) | PIK3CAHDAC1MTORADORA1TLR7 | |
| SCHEMBL30439903 | 0.82 | TLR7 (0.50) | PIK3CANT5ESMN1; SMN2HDAC1MTOR | |
| SCHEMBL2395003 | 0.82 | TLR7 (0.50) | PIK3CANT5ESMN1; SMN2HDAC1MTOR | |
| Hydrochloric Acid SCHEMBL7330227 | 0.82 | CDK1 (0.50) | PIK3CACDK1YTHDC1ADORA1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119031913-A | Purine and methods of use thereof | 奇尼塔公司 | 2024-11-26 | — | — | CN | disclosed |
| CN-112920199-B | Piperazinone substituent or derivative thereof, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-02-03 | — | — | CN | disclosed |