SCHEMBL30366138

SCHEMBL30366138

CC(C)Cc1cc(C2(c3cc(CC(C)C)c(OCCO)c(CC(C)C)c3)c3ccccc3-c3ccccc32)cc(CC(C)C)c1OCCO

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 12/20 0.39
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
KDM4E B2RXH2 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MCHR1 Q99705 1/20 0.32
ALDH1A1 P00352 2/20 0.32
RECQL P46063 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL383342 1.00 PDK2 (0.39) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL30064119 0.85 PDK2 (0.41) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL382493 0.85 PDK2 (0.41) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL29632696 0.85 ESR1 (0.41) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL382896 0.85 ESR1 (0.41) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL383683 0.83 PDK2 (0.40) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL383832 0.82 PDK2 (0.40) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL30366351 0.82 PDK2 (0.40) PDK2ESR1ESR2KDM4EMEN1
SCHEMBL382750 0.81 PDK2 (0.40) PDK2ESR1ESR2KDM4E
SCHEMBL30366086 0.81 PDK2 (0.40) PDK2ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113423757-B Polycarbonate resin composition or copolymer, and optical film 帝人株式会社 2023-04-04 CN disclosed