Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.81 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.81 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.81 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.68 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597636 | 1.00 | PIK3CD (0.81) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL2468696 | 0.90 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL29381409 | 0.90 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL30808305 | 0.90 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL994581 | 0.89 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL28605015 | 0.88 | PIK3CD (0.68) | PIK3CDPIK3CAPIK3CBPIK3R1PIK3CG | |
| SCHEMBL28597637 | 0.84 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL994792 | 0.84 | PIK3CD (0.83) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL13640270 | 0.83 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 | |
| SCHEMBL2519277 | 0.83 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CBPIK3R1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920199-B | Piperazinone substituent or derivative thereof, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-02-03 | — | — | CN | disclosed |