SCHEMBL30366299

SCHEMBL30366299

CC(C)(C)OC(=O)N1CC(=O)N(CCO[Si](C)(C)C(C)(C)C)c2c1ccc(F)c2CC=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
PARP1 P09874 1/20 0.32
PARP2 Q9UGN5 1/20 0.32
SCN5A Q14524 1/20 0.31
SCN9A Q15858 1/20 0.31
GPR119 Q8TDV5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21820343 1.00 HDAC1 (0.36) HDAC1HDAC6PARP1PARP2SCN5A
SCHEMBL21820259 0.92 HDAC1 (0.36) HDAC1HDAC6PARP1PARP2SCN5A
SCHEMBL30366260 0.92 HDAC1 (0.36) HDAC1HDAC6PARP1PARP2SCN5A
SCHEMBL25015254 0.91 HDAC1 (0.37) HDAC1HDAC6SCN5ASCN9AGPR119
SCHEMBL28980752 0.90 PARP1 (0.31) PARP1PARP2
SCHEMBL20582419 0.85 HDAC1 (0.40) HDAC1HDAC6PARP1PARP2SCN5A
SCHEMBL30366161 0.85 HDAC1 (0.40) HDAC1HDAC6PARP1PARP2SCN5A
SCHEMBL25015076 0.83 HDAC1 (0.37) HDAC1HDAC6SCN5ASCN9A
SCHEMBL28980754 0.82 PARP1 (0.31) PARP1PARP2
SCHEMBL28980756 0.75 PARP1 (0.34) PARP1PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382505-B Heterocyclic compounds useful as antibacterial agents and process for producing the same 巴格沃克斯研究有限公司 2023-04-04 CN disclosed