Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 13/20 | 0.69 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.67 |
| ▸ | PIK3R1 | P27986 | 7/20 | 0.67 |
| ▸ | MTOR | P42345 | 4/20 | 0.62 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28597630 | 1.00 | PIK3CD (0.69) | PIK3CDPIK3CAPIK3R1MTORPIK3CB | |
| SCHEMBL28918295 | 0.91 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL2674625 | 0.84 | PIK3CD (0.62) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2673524 | 0.84 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL190336 | 0.83 | PIK3CD (0.86) | PIK3CDPIK3CAPIK3R1PIK3CBPIK3CG | |
| SCHEMBL2675377 | 0.83 | PIK3CD (0.70) | PIK3CDPIK3CA | |
| SCHEMBL2674722 | 0.82 | PIK3CD (0.63) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2674338 | 0.82 | PIK3CD (1.00) | PIK3CDPIK3CA | |
| SCHEMBL2674154 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3CA | |
| SCHEMBL1867881 | 0.80 | PIK3CA (0.66) | PIK3CDPIK3CAPIK3R1MTORPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920199-B | Piperazinone substituent or derivative thereof, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-02-03 | — | — | CN | disclosed |