Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | TEK | Q02763 | 2/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28981099 | 0.84 | BTK (0.39) | BTKFFAR4KDRTEKLCK | |
| SCHEMBL30366701 | 0.81 | BTK (0.36) | BTKFFAR4 | |
| SCHEMBL30366769 | 0.80 | KDR (0.35) | FFAR4KDRTEKLCK | |
| SCHEMBL30366523 | 0.77 | KDR (0.33) | FFAR4KDRTEKLCK | |
| SCHEMBL28981103 | 0.76 | BTK (0.35) | BTKPRMT5 | |
| SCHEMBL30325807 | 0.76 | BTK (0.40) | BTK | |
| SCHEMBL30366804 | 0.76 | CYP3A4 (0.47) | BTKFFAR4KDRTEK | |
| SCHEMBL30366502 | 0.75 | CYP3A4 (0.42) | BTKFFAR4KDRTEK | |
| SCHEMBL31411040 | 0.75 | LCK (0.41) | BTKKDRTEKLCK | |
| SCHEMBL22678110 | 0.75 | LCK (0.41) | BTKKDRTEKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |