Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788798 | 0.83 | SETD7 (0.47) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3037280 | 0.83 | SETD7 (0.53) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3046586 | 0.82 | SETD7 (0.52) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3134006 | 0.79 | CYP2D6 (0.49) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL14693488 | 0.76 | KDM4E (0.71) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3040906 | 0.73 | MAPK1 (0.47) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3040904 | 0.73 | MAPK1 (0.47) | SETD7KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL3034892 | 0.73 | KDM4E (0.65) | SETD7KDM4EHSD17B10MAPTKMT2A | |
| SCHEMBL3044099 | 0.72 | KDM4E (0.55) | SETD7KDM4EMAPTKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3049107 | 0.72 | SETD7 (0.52) | SETD7KDM4EMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243778-A1 | PIPERIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |