Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.77 |
| ▸ | DDB1 | Q16531 | 15/20 | 0.77 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL1B | P01584 | 1/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.59 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CCNK | O75909 | 1/20 | 0.55 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.55 |
| ▸ | CDK2 | P24941 | 1/20 | 0.55 |
| ▸ | CDK9 | P50750 | 1/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366756 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30366849 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30534880 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30366807 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25224286 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25220504 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24133684 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL25219673 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL28981117 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL26917599 | 1.00 | CRBN (0.77) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894506-B | Chimeric molecule and preparation method and application thereof | 四川大学 | 2025-03-18 | — | — | CN | disclosed |
| CN-115894506-A | Chimeric molecule and preparation method and application thereof | 四川大学 | 2023-04-04 | — | — | CN | disclosed |