Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 14/20 | 0.77 |
| ▸ | EHMT1 | Q9H9B1 | 12/20 | 0.77 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476777 | 1.00 | EHMT2 (0.77) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL19476447 | 0.94 | EHMT2 (0.78) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL19477091 | 0.87 | EHMT2 (0.96) | EHMT2EHMT1BRD4IGF1RDOT1L | |
| SCHEMBL19477197 | 0.87 | EHMT2 (1.00) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL25620037 | 0.87 | EHMT2 (0.58) | EHMT2EHMT1BRD4DOT1LNPC1 | |
| SCHEMBL21743465 | 0.86 | EHMT2 (0.98) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL21743854 | 0.86 | EHMT2 (0.98) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL19462311 | 0.83 | EHMT2 (0.78) | EHMT2EHMT1BRD4EGFRIGF1R | |
| SCHEMBL19477306 | 0.83 | EHMT2 (0.78) | EHMT2EHMT1BRD4IGF1RDOT1L | |
| SCHEMBL25623836 | 0.83 | EHMT2 (0.61) | EHMT2EHMT1BRD4IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |