Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.63 |
| ▸ | PI4KA | P42356 | 2/20 | 0.63 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.63 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.63 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.63 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.63 |
| ▸ | DPP4 | P27487 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.63 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.63 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.63 |
| ▸ | GAPDH | P04406 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.63 |
| ▸ | STAT6 | P42226 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.63 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26130576 | 1.00 | ADORA2A (0.79) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL546470 | 0.89 | ADORA2A (0.77) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL17440175 | 0.89 | ADORA2A (0.77) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL19402567 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL21006596 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL24838594 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL12150780 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL21081913 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5559348 | 0.88 | ADORA2A (0.79) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL14842184 | 0.88 | ADORA2A (1.00) | ADORA2AADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223620-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2025-07-10 | — | — | US | disclosed |
| EP-4504932-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GlaxoSmithKline Intellectual Property Development Ltd (GB) | 2025-02-12 | — | — | EP | disclosed |
| CN-119013398-A | Novel method for producing polynucleotides comprising oligonucleotides | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-11-22 | — | — | CN | disclosed |
| WO-2023194537-A1 | NOVEL PROCESSES FOR THE PRODUCTION OF POLYNUCLEOTIDES INCLUDING OLIGONUCLEOTIDES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-12 | — | — | WO | disclosed |
| CN-115997020-A | Novel nucleic acid ligands and methods for identifying same | 因特欧力多公司 | 2023-04-21 | — | — | CN | disclosed |