Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 10/20 | 0.75 |
| ▸ | EHMT1 | Q9H9B1 | 9/20 | 0.75 |
| ▸ | IGF1R | P08069 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19476592 | 1.00 | EHMT2 (0.75) | EHMT2EHMT1IGF1R | |
| SCHEMBL19474459 | 0.88 | EHMT2 (0.58) | EHMT2EHMT1IGF1R | |
| SCHEMBL19476361 | 0.86 | EHMT2 (0.79) | EHMT2EHMT1IGF1R | |
| SCHEMBL25613448 | 0.86 | EHMT2 (0.79) | EHMT2EHMT1IGF1R | |
| SCHEMBL19477197 | 0.86 | EHMT2 (1.00) | EHMT2EHMT1IGF1R | |
| SCHEMBL19477304 | 0.86 | EHMT2 (0.79) | EHMT2EHMT1IGF1R | |
| SCHEMBL19476681 | 0.85 | EHMT2 (0.67) | EHMT2EHMT1IGF1R | |
| SCHEMBL21743465 | 0.85 | EHMT2 (0.98) | EHMT2EHMT1IGF1R | |
| SCHEMBL21743854 | 0.85 | EHMT2 (0.98) | EHMT2EHMT1IGF1R | |
| SCHEMBL19477276 | 0.85 | EHMT2 (0.84) | EHMT2EHMT1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |