Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26967859 | 1.00 | NR1H2 (0.61) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL1626377 | 0.88 | NR1H2 (0.62) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL29812142 | 0.88 | NR1H2 (0.62) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL348414 | 0.86 | NR1H2 (0.61) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL7362801 | 0.84 | POLB (0.60) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL5206808 | 0.83 | POLB (0.58) | NR1H2NR1H3POLBSMN1; SMN2CYP3A4 | |
| SCHEMBL28860295 | 0.83 | POLB (0.58) | NR1H2NR1H3POLBSMN1; SMN2TDP1 | |
| SCHEMBL9430272 | 0.82 | CYP3A4 (0.53) | POLBSMN1; SMN2CYP3A4TDP1CA12 | |
| SCHEMBL30843858 | 0.82 | CYP3A4 (0.53) | POLBSMN1; SMN2CYP3A4TDP1CA12 | |
| SCHEMBL3191583 | 0.81 | SMN1; SMN2 (0.61) | NR1H2NR1H3POLBSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117440951-A | Pyridone compounds and methods of use | 埃克塞里艾克西斯公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |