Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 12/20 | 0.82 |
| ▸ | EHMT1 | Q9H9B1 | 10/20 | 0.82 |
| ▸ | IGF1R | P08069 | 1/20 | 0.53 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19462213 | 1.00 | EHMT2 (0.82) | EHMT2EHMT1IGF1RDNMT1EGFR | |
| SCHEMBL19477197 | 0.90 | EHMT2 (1.00) | EHMT2EHMT1IGF1RDNMT1EGFR | |
| SCHEMBL21743854 | 0.89 | EHMT2 (0.98) | EHMT2EHMT1IGF1REGFRSRC | |
| SCHEMBL19462308 | 0.89 | EHMT2 (0.81) | EHMT2EHMT1IGF1REGFRMCHR1 | |
| SCHEMBL21743465 | 0.89 | EHMT2 (0.98) | EHMT2EHMT1IGF1REGFRSRC | |
| SCHEMBL19477281 | 0.89 | EHMT2 (0.79) | EHMT2EHMT1IGF1REGFRMCHR1 | |
| SCHEMBL19477284 | 0.89 | EHMT2 (0.79) | EHMT2EHMT1IGF1R | |
| SCHEMBL19476331 | 0.89 | EHMT2 (0.79) | EHMT2EHMT1IGF1REGFRMCHR1 | |
| SCHEMBL19477091 | 0.88 | EHMT2 (0.96) | EHMT2EHMT1IGF1RDNMT1 | |
| SCHEMBL19477087 | 0.88 | EHMT2 (0.78) | EHMT2EHMT1IGF1REGFRMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3442947-B1 | AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS | EPIZYME INC (US) | 2023-06-07 | — | — | EP | disclosed |