Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19796135 | 1.00 | KDM4E (0.45) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL18393520 | 1.00 | KDM4E (0.45) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL18393890 | 0.78 | KDM4E (0.48) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL19803916 | 0.77 | KDM4E (0.47) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL492334 | 0.75 | KDM4E (0.45) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL28649279 | 0.75 | — | — | |
| SCHEMBL492442 | 0.73 | KDM4E (0.44) | KDM4EGAATDP1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL492462 | 0.72 | KDM4E (0.42) | KDM4EGAATDP1LMNACYP1A2 | |
| SCHEMBL18394140 | 0.72 | KDM4E (0.57) | KDM4EGAATDP1LMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL492457 | 0.72 | KDM4E (0.42) | KDM4EGAATDP1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114514223-B | Process for enantioselective hydrogenation of 4-substituted 1, 2-dihydroquinolines comprising using novel iridium catalysts | 拜耳公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-116082415-A | Ferrocene amino bidentate phosphine ligand compound and preparation method and application thereof | 中国海洋石油集团有限公司 | 2023-05-09 | — | — | CN | disclosed |