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SCHEMBL30368454

SCHEMBL30368454

NCCCC[C@H](NC(=O)[C@H](CCN)NC(=O)[C@H](CS)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 4/20 0.55
▸ NPY1R P25929 3/20 0.55
▸ NPY2R P49146 3/20 0.55
▸ MME P08473 4/20 0.51
▸ ERAP2 Q6P179 1/20 0.49
▸ LNPEP Q9UIQ6 1/20 0.49
▸ NPY5R Q15761 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30183809 1.00 NPY4R (0.55) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30367620 1.00 NPY4R (0.55) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30882680 1.00 NPY4R (0.55) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30361704 0.99 NPY4R (0.54) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30183642 0.98 NPY4R (0.58) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30367693 0.96 NPY4R (0.52) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL30368238 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RMMEERAP2
SCHEMBL32672641 0.95 MME (0.56) NPY4RNPY1RNPY2RMME
SCHEMBL32672550 0.95 MME (0.56) NPY4RNPY1RNPY2RMME
SCHEMBL30368083 0.94 NPY4R (0.66) NPY4RNPY1RNPY2RERAP2NPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115989236-A Antimicrobial peptidomimetics 斯派西斯公司 2023-04-18 — — CN claimed
CN-115989236-A Antimicrobial peptidomimetics 斯派西斯公司 2023-04-18 — — CN disclosed