SCHEMBL30368635

SCHEMBL30368635

CCN(CC)CCCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 20/20 1.00
▸ FGFR2 P21802 6/20 1.00
▸ FGFR4 P22455 6/20 1.00
▸ FGFR3 P22607 6/20 1.00
▸ EGFR P00533 5/20 1.00
▸ SRC P12931 5/20 1.00
▸ PRKD3 O94806 2/20 1.00
▸ PRKCG P05129 2/20 1.00
▸ PRKCB P05771 2/20 1.00
▸ PRKCA P17252 2/20 1.00
▸ PRKCH P24723 2/20 1.00
▸ PRKCI P41743 2/20 1.00
▸ PRKCE Q02156 2/20 1.00
▸ PRKCQ Q04759 2/20 1.00
▸ PRKCZ Q05513 2/20 1.00
▸ PRKCD Q05655 2/20 1.00
▸ PRKD1 Q15139 2/20 1.00
▸ KDR P35968 2/20 0.75
▸ GLA P06280 1/20 0.70
▸ FLT1 P17948 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4301366 1.00 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL29375761 1.00 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL145351 0.98 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL144578 0.94 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL144075 0.90 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL148438 0.89 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL143775 0.89 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL142058 0.89 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL145287 0.88 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR
SCHEMBL146740 0.88 FGFR1 (1.00) FGFR1FGFR2FGFR4FGFR3EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355110-A Method for producing cartilage and bone 默多克儿童研究所 2024-07-16 — — CN claimed
EP-4680255-A1 METHODS FOR PRODUCING STABLE HUMAN CHONDROCTYES AND THEIR USE FOR PROMOTING CARTILLAGE GROWTH AND REPAIR The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2026-01-21 — — EP disclosed
US-20250270507-A1 METHODS FOR PRODUCING CARTILAGE AND BONES MURDOCH CHILDREN'S RESEARCH INSTITUTE OF THE ROYAL CHILDREN'S HOSPITAL (AU) 2025-08-28 — — US disclosed
WO-2024192329-A1 METHODS FOR PRODUCING STABLE HUMAN CHONDROCTYES AND THEIR USE FOR PROMOTING CARTILLAGE GROWTH AND REPAIR THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-09-19 — — WO disclosed
EP-4416268-A1 METHODS FOR PRODUCING CARTILAGE AND BONES Murdoch Children's Research Institute (AU) 2024-08-21 — — EP disclosed
CN-118355110-A Method for producing cartilage and bone 默多克儿童研究所 2024-07-16 — — CN disclosed
WO-2023060322-A1 METHODS FOR PRODUCING CARTILAGE AND BONES MURDOCH CHILDREN'S RESEARCH INSTITUTE (AU) 2023-04-20 — — WO disclosed
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