Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 1.00 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.78 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.78 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.78 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.78 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.78 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.78 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.78 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.78 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.78 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20534798 | 1.00 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20534984 | 0.88 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20534699 | 0.84 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30396047 | 0.82 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20534876 | 0.82 | HDAC6 (0.70) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20534704 | 0.82 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL30395669 | 0.82 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL23317003 | 0.81 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL29640425 | 0.81 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL20535631 | 0.81 | HDAC6 (1.00) | HDAC6HDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562810-B1 | BENZHYDROXAMIC ACID DERIVATIVES AS SELECTIVE HDAC6 INHIBITORS | ITALFARMACO SPA (IT) | 2023-05-03 | — | — | EP | claimed |