Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 15/20 | 0.52 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | IL1B | P01584 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368918 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL30369004 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL21622008 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL24080038 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL30368896 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL24080122 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL30369208 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL24079912 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL21618188 | 1.00 | IKZF2 (0.52) | IKZF2CRBNIKZF1BRD4TNF | |
| SCHEMBL21621900 | 0.89 | CRBN (0.54) | IKZF2CRBNIKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119241499-A | 3- (5-Hydroxy-1-oxo-isoindolin-2-yl) piperidine-2, 6-dione derivatives and uses thereof | 诺华股份有限公司 | 2025-01-03 | — | — | CN | claimed |
| CN-116096862-A | ZBTB32 inhibitors and uses thereof | 诺华股份有限公司 | 2023-05-09 | — | — | CN | disclosed |