Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 7/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 7/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22426348 | 1.00 | HIF1A (0.47) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL26275114 | 0.90 | HIF1A (0.43) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426417 | 0.90 | HIF1A (0.43) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426413 | 0.89 | KMT2A (0.49) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL28515964 | 0.89 | MEN1 (0.56) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426426 | 0.89 | BAZ2B (0.41) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426381 | 0.89 | GAA (0.41) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL30118923 | 0.89 | GAA (0.41) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426451 | 0.87 | GAA (0.46) | HIF1AEPAS1BAZ2BBAZ2AGAA | |
| SCHEMBL22426473 | 0.87 | HIF1A (0.41) | HIF1AEPAS1BAZ2BBAZ2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168408-A1 | COMPOUNDS FOR AND METHODS OF TREATING DISEASES | Alterity Therapeutics Limited (AU) | 2023-04-26 | — | — | EP | disclosed |