Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 6/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.38 |
| ▸ | MTOR | P42345 | 3/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | STK4 | Q13043 | 1/20 | 0.35 |
| ▸ | STK3 | Q13188 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23815376 | 1.00 | PIK3CD (0.40) | PIK3CDPIK3CAMTORGRIN2BAVPR1B | |
| SCHEMBL23815458 | 0.91 | PIK3CA (0.41) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL30370156 | 0.91 | PIK3CA (0.41) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL30369994 | 0.89 | MTOR (0.40) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL23815382 | 0.89 | MTOR (0.40) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL23815377 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL30369983 | 0.89 | PIK3CD (0.39) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL23815459 | 0.88 | MTOR (0.39) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL30370241 | 0.88 | MTOR (0.39) | PIK3CDPIK3CAMTORGRIN2BEGLN1 | |
| SCHEMBL23804690 | 0.88 | EGLN1 (0.43) | PIK3CDPIK3CAMTORGRIN2BEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230146395-A1 | Substituted Pyrimidines and Uses Thereof | Verge Analytics, Inc. (US) | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230146395-A1 | Substituted Pyrimidines and Uses Thereof | PIKFYVE, PIK3CA, PIK3CB | PIK3CD 4/4885PIK3CA 2/4885MTOR 172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.