SCHEMBL3037031

SCHEMBL3037031

CCCCCCCCc1ccc(-c2ncncn2)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.51
KAT8 Q9H7Z6 2/20 0.48
ESR1 P03372 2/20 0.47
ADRA2A P08913 2/20 0.47
ADORA3 P0DMS8 2/20 0.47
TACR2 P21452 2/20 0.47
SLC6A2 P23975 2/20 0.47
SLC6A4 P31645 2/20 0.47
SLC6A3 Q01959 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
LMNA P02545 1/20 0.47
SHBG P04278 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
HSPD1 P10809 1/20 0.47
ADRB3 P13945 1/20 0.47
HTR2C P28335 1/20 0.47
HSPE1 P61604 1/20 0.47
HIF1A Q16665 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28132783 1.00 PPARA (0.51) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL9251058 0.87 PPARA (0.52) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL9331383 0.87 PPARA (0.52) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL28245278 0.84 PPARA (0.56) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL29973326 0.84 PPARA (0.56) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL28132653 0.84 PPARA (0.56) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL22410814 0.84 PPARA (0.56) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL28246423 0.84 PPARA (0.56) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL340034 0.82 PPARA (0.65) PPARAKAT8ESR1ADRA2AADORA3
SCHEMBL340476 0.82 PPARA (0.65) PPARAKAT8ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8318980-B2 UV absorbing compounds FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2012-11-27 US disclosed
US-20100209366-A1 UV ABSORBING COMPOUNDS FUJIFILM MANUFACTURING EUROPE B.V. 2010-08-19 US disclosed
CN-1852697-A Use of halogenated hydroxydiphenyl ether compounds for the treatment of the skin CIBA SC HOLDING AG (CH) 2006-10-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100209366-A1 UV ABSORBING COMPOUNDS CCNA2, UBE2G2, MCM7 PPARA 4244/4885KAT8 1986/4885ESR1 1749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.