Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 14/20 | 0.71 |
| ▸ | ESR1 | P03372 | 13/20 | 0.71 |
| ▸ | ESR2 | Q92731 | 13/20 | 0.71 |
| ▸ | TOP1 | P11387 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30374803 | 0.94 | HRAS (0.69) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL30374497 | 0.88 | HRAS (0.62) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL30469493 | 0.87 | HRAS (0.79) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL5889511 | 0.85 | HRAS (0.69) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL7510361 | 0.85 | HRAS (0.76) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL30768134 | 0.85 | HRAS (0.69) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL9124388 | 0.84 | KDM4E (0.76) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL10688614 | 0.84 | KDM4E (0.76) | HRASESR1ESR2TOP1KDM4E | |
| Hydrochloric Acid SCHEMBL6548715 | 0.84 | KDM4E (0.76) | HRASESR1ESR2TOP1KDM4E | |
| SCHEMBL29394871 | 0.84 | HRAS (0.78) | HRASESR1ESR2TOP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023052772-A1 | AMIDO DERIVATIVES FOR USE IN THE TREATMENT OF RNA VIRAL INFECTIONS | UNIVERSITY OF STRATHCLYDE (GB) | 2023-04-06 | — | — | WO | disclosed |