Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3519494 | 1.00 | CYP3A4 (0.54) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL1722920 | 0.85 | TSHR (0.50) | ATMKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL29472049 | 0.85 | TSHR (0.50) | ATMKMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL24196489 | 0.81 | NPC1 (0.49) | ALDH1A1TDP1ATMKMT2AMAPT | |
| SCHEMBL5682293 | 0.75 | CYP3A4 (0.54) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL4606902 | 0.75 | CYP3A4 (0.54) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL1045633 | 0.75 | CYP3A4 (0.54) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL6351358 | 0.73 | CYP3A4 (0.52) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL1486215 | 0.72 | CYP3A4 (0.56) | CYP3A4ALDH1A1MAPK1HSD17B10TDP1 | |
| SCHEMBL21451034 | 0.72 | MEN1 (0.59) | CYP3A4ALDH1A1MAPK1HSD17B10SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4582423-A1 | NOVEL TRICYCLIC DERIVATIVE COMPOUND AND USES THEREOF | Hanmi Pharm. Co., Ltd. (KR) | 2025-07-09 | — | — | EP | disclosed |
| CN-120077041-A | Tricyclic derivative compounds and use thereof | 韩美药品株式会社 | 2025-05-30 | — | — | CN | disclosed |
| EP-4426681-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | Sitryx Therapeutics Limited (GB) | 2024-09-11 | — | — | EP | disclosed |
| WO-2023079294-A1 | PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS | SITRYX THERAPEUTICS LIMITED (GB) | 2023-05-11 | — | — | WO | disclosed |