SCHEMBL3037601

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3112016	0.93	AKT1 (0.61)	AKT1AKT2NTRK1CSNK1E
	SCHEMBL3356986	0.86	AKT1 (0.55)	AKT1AKT2NTRK1CSNK1ECHRM1
	SCHEMBL3104269	0.83	AKT1 (0.52)	AKT1AKT2NTRK1CSNK1E
	SCHEMBL12985803	0.83	AKT1 (1.00)	AKT1AKT2CHRM1FLT1CLK1
	SCHEMBL10277362	0.82	AKT1 (0.50)	AKT1AKT2NTRK1MEN1USP2
	SCHEMBL3115930	0.82	NTRK1 (0.50)	AKT1AKT2NTRK1HPGDSMN1; SMN2
	SCHEMBL4911963	0.78	NTRK1 (0.56)	AKT1AKT2NTRK1HPGDSMN1; SMN2
	SCHEMBL10531829	0.78	AKT1 (0.47)	AKT1AKT2NTRK1MEN1HPGD
	SCHEMBL31704285	0.76	AKT1 (0.53)	AKT1AKT2CSNK1ECHRM1FLT1
	SCHEMBL4968666	0.75	NTRK1 (0.53)	AKT1AKT2NTRK1CHRM1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.