Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 19/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 19/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23539324 | 0.89 | DDB1 (0.59) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23799146 | 0.88 | DDB1 (0.55) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23783169 | 0.85 | DDB1 (0.52) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL31329731 | 0.85 | DDB1 (0.55) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL31323646 | 0.85 | DDB1 (0.63) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL30919585 | 0.85 | DDB1 (0.52) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL31323602 | 0.83 | DDB1 (0.52) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL31323836 | 0.83 | DDB1 (0.57) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL30207617 | 0.83 | DDB1 (0.53) | DDB1CRBNHDAC3HDAC1HDAC2 | |
| SCHEMBL23797599 | 0.83 | DDB1 (0.60) | DDB1CRBNHDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4168407-A1 | BRAF DEGRADERS | C4 Therapeutics, Inc. (US) | 2023-04-26 | — | — | EP | disclosed |