⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL6160661 | 0.96 | TSHR (0.64) | — | |
| Pyridine SCHEMBL28322715 | 0.96 | TSHR (0.64) | — | |
| Pyridine SCHEMBL1095589 | 0.93 | NAPRT (0.60) | — | |
| Pyridine SCHEMBL11485834 | 0.93 | TSHR (0.60) | — | |
| Pyridine SCHEMBL8332035 | 0.90 | TSHR (0.56) | — | |
| Pyridine SCHEMBL367049 | 0.89 | TSHR (0.64) | — | |
| Pyridine SCHEMBL31396433 | 0.88 | — | — | |
| Pyridine SCHEMBL28773703 | 0.87 | TSHR (0.53) | — | |
| Pyridine SCHEMBL4354686 | 0.86 | — | — | |
| Pyridine SCHEMBL9123929 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 967 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024132278-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | UNIVERSITÄT REGENSBURG (DE) | 2024-06-27 | — | — | WO | claimed |
| EP-4389223-A1 | SYNTHESIS, PHARMACOLOGY AND USE OF NEW WATER-SOLUBLE AND SELECTIVE FMS-LIKE TYROSINE KINASE 3 (FLT3) INHIBITORS | Universität Regensburg (DE) | 2024-06-26 | — | — | EP | claimed |
| CN-117797788-A | Oil-soluble iron adsorbent and synthetic method and application thereof | 西安热工研究院有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117323439-A | Nanometer preparation of co-carrying salinomycin and gene medicine, preparation method and application thereof | 中日友好医院(中日友好临床医学研究所) | 2024-01-02 | — | — | CN | claimed |
| CN-116832860-A | Preparation method and application of high-molecular supported NHPI and sulfonic acid group bifunctional catalyst | 湘潭大学 | 2023-10-03 | — | — | CN | claimed |
| CN-116377016-A | High-voltage insulating material mold pollution cleaning system and method | 华北电力大学（保定） | 2023-07-04 | — | — | CN | claimed |
| CN-114456124-B | New cilastatin hapten, artificial antigen, antibody and preparation method and application thereof | 华南农业大学 | 2023-04-21 | — | — | CN | claimed |
| CN-112457363-B | Potato trisaccharide oleanolic acid saponin derivative and preparation method and application thereof | 华南农业大学 | 2021-12-24 | — | — | CN | claimed |
| CN-110028547-A | A kind of diosgenin 3-OH derivative and preparation method thereof and medical usage | 中国药科大学 | 2019-07-19 | — | — | CN | claimed |
| CN-106727307-B | A kind of preparation and application restoring sensitive nano-micelle | 江苏师范大学 | 2019-07-02 | — | — | CN | claimed |
| CN-101163688-A | A process for the purification of 10-deacetylbaccatine iii from 10-de acet yl-2- debenzoyl-2-pentenoylbaccatine iii | INDENA SPA (IT) | 2008-04-16 | — | — | CN | claimed |
| EP-1192162-B1 | TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | INDENA SPA (IT) | 2004-09-29 | — | — | EP | claimed |
| US-6750335-B2 | NUCLEOSIDE FOR USE IN THE GENERATION OF PREFERENTIAL OLIGONUCEOTIDES | NIGU CHEMIE GMBH (DE) | 2004-06-15 | — | — | US | claimed |
| US-20020146737-A1 | Nucleoside derivatives with photolabile protective groups | NIGU CHEMIE GMBH (DE) | 2002-10-10 | — | — | US | claimed |
| EP-1192162-A2 | TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | INDENA S.p.A. (IT) | 2002-04-03 | — | — | EP | claimed |
| WO-2001002407-A2 | TAXANE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | INDENA S.P.A. (IT) | 2001-01-11 | — | — | WO | claimed |
| US-5705660-A | Method for the synthesis of α-oxiranyl amino acids | BOARD OF REGENTS, UNIVERSITY OF NEBRASKA-LINCOLN | 1998-01-06 | — | — | US | claimed |
| US-5585470-A | Process for the manufacture of 3-amino-substituted glycosylated bile acids | TRANSCELL TECHNOLOGIES, INC. (US) | 1996-12-17 | — | — | US | claimed |
| EP-0264183-B1 | DERIVATIVES OF 5-METHYL-10,11-DIHYDRO-5H-DIBENZO-(A,D) CYCLOHEPTEN-5,10-IMINE | MERCK & CO. INC. (US) | 1992-01-15 | — | — | EP | claimed |
| EP-0372157-A1 | Antidiabetic phosphonates | AMERICAN CYANAMID COMPANY (US) | 1990-06-13 | — | — | EP | claimed |