Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | STK17B | O94768 | 1/20 | 0.40 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29000784 | 1.00 | POLB (0.45) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30379157 | 0.89 | POLB (0.44) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29000713 | 0.89 | POLB (0.44) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30379817 | 0.88 | POLB (0.44) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29000758 | 0.88 | POLB (0.44) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2061981 | 0.85 | FGFR1 (0.53) | POLBKMT2AMEN1SMN1; SMN2EGFR | |
| SCHEMBL28360041 | 0.85 | EGFR (0.41) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL30379924 | 0.85 | FGFR1 (0.46) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL29000763 | 0.85 | FGFR1 (0.46) | POLBPLK1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL24625782 | 0.85 | EGFR (0.45) | SMN1; SMN2EGFRFGFR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120300-B | Pyrimidine compound containing hydroxamic acid fragment, and preparation method and application thereof | 贵州大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-116120300-A | Pyrimidine compound containing hydroxamic acid fragment, and preparation method and application thereof | 贵州大学 | 2023-05-16 | — | — | CN | disclosed |