Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.73 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 6/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24593725 | 1.00 | KDM4E (0.73) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL1232929 | 0.90 | MAOB (0.66) | KDM4EMAPTRAB9ANPC1MAOB | |
| SCHEMBL1232928 | 0.90 | MAOB (0.66) | KDM4EMAPTRAB9ANPC1MAOB | |
| SCHEMBL30579629 | 0.90 | MAOB (0.66) | KDM4EMAPTRAB9ANPC1MAOB | |
| SCHEMBL2730201 | 0.85 | KDM4E (1.00) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL2730205 | 0.85 | KDM4E (1.00) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL10793430 | 0.83 | KDM4E (0.73) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL10793426 | 0.83 | KDM4E (0.73) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL3209529 | 0.83 | KDM4E (0.73) | KDM4ECXCL12MAPTRAB9ANPC1 | |
| SCHEMBL3209559 | 0.83 | KDM4E (0.73) | KDM4ECXCL12MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023055020-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING VASCULAR DISEASES, COMPRISING PIPERLONGUMINE-BASED COMPOUND AS ACTIVE INGREDIENT | 주성수 | 2023-04-06 | — | — | WO | disclosed |