Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380292 | 1.00 | CA14 (0.36) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL30380396 | 1.00 | CA14 (0.36) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL30380680 | 1.00 | CA14 (0.36) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL30381232 | 1.00 | CA14 (0.36) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL24701120 | 0.86 | CA14 (0.35) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL19243675 | 0.86 | CA14 (0.35) | CA14KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL18739284 | 0.84 | CA14 (0.36) | CA14KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL2543733 | 0.83 | CA14 (0.41) | CA14GAAMEN1KMT2ADGAT1 | |
| SCHEMBL20365461 | 0.81 | NR1I2 (0.36) | CA14DGAT1L3MBTL1BLMPMP22 | |
| SCHEMBL30244620 | 0.81 | MEN1 (0.39) | CA14ALDH1A1MEN1KMT2ADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059583-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |