Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458774 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL20548054 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL30008141 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL30380581 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL30244578 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL25334266 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL21458406 | 1.00 | F2 (0.38) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL1649505 | 0.93 | F2 (0.40) | F2STAT3PDK2CA12CA1 | |
| SCHEMBL19451333 | 0.89 | F2 (0.39) | F2STAT3CA12CA1CA9 | |
| SCHEMBL14707434 | 0.89 | F2 (0.39) | F2STAT3CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059583-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |