Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 14/20 | 0.51 |
| ▸ | TLR7 | Q9NYK1 | 14/20 | 0.51 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24120760 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL24120789 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL30381943 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL30381265 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL24120681 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL24120684 | 1.00 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL25702229 | 0.93 | TLR9 (0.45) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL24120570 | 0.92 | TLR9 (0.54) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL25700412 | 0.92 | TLR9 (0.54) | TLR9TLR7TLR8HRH1HRH3 | |
| SCHEMBL24120542 | 0.92 | TLR9 (0.51) | TLR9TLR7TLR8HRH1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3856737-B1 | HETEROCYCLYL COMPOUNDS FOR THE TREATMENT OF AUTOIMMUNE DISEASE | HOFFMANN LA ROCHE (CH) | 2023-05-17 | — | — | EP | disclosed |