SCHEMBL30382487

SCHEMBL30382487

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1COc1cccc(Cl)c1Cl

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 7/20 0.67
▸ KMT2A Q03164 7/20 0.67
▸ LMNA P02545 4/20 0.67
▸ ALDH1A1 P00352 4/20 0.67
▸ KDM4E B2RXH2 2/20 0.67
▸ MAPT P10636 5/20 0.62
▸ SMN1; SMN2 Q16637 2/20 0.62
▸ THRB P10828 1/20 0.62
▸ CTSL P07711 1/20 0.55
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ RECQL P46063 1/20 0.53
▸ CXCL12 P48061 3/20 0.52
▸ POLB P06746 1/20 0.52
▸ ABCG2 Q9UNQ0 1/20 0.51
▸ CA1 P00915 1/20 0.51
▸ CA2 P00918 1/20 0.51
▸ CXCR4 P61073 1/20 0.50
▸ DPP4 P27487 1/20 0.50
▸ NR1H4 Q96RI1 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25194782 1.00 MEN1 (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25197334 0.92 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383576 0.92 MEN1 (0.70) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30384712 0.90 MEN1 (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25212438 0.90 MEN1 (0.67) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25196256 0.87 CYP19A1 (0.62) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30383592 0.87 CYP19A1 (0.62) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25197364 0.87 MEN1 (0.68) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL25185030 0.86 MEN1 (0.76) MEN1KMT2ALMNAALDH1A1KDM4E
SCHEMBL30384858 0.86 MEN1 (0.76) MEN1KMT2ALMNAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 — — WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 — — EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 — — WO disclosed
Send feedback