Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.42 |
| ▸ | BACE1 | P56817 | 7/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MERTK | Q12866 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.37 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038261 | 1.00 | TTK (0.42) | TTKBACE1PRKDCCSF1RMERTK | |
| SCHEMBL3036644 | 0.98 | BACE1 (0.43) | TTKBACE1PRKDCCSF1RMERTK | |
| SCHEMBL3036637 | 0.98 | BACE1 (0.43) | TTKBACE1PRKDCCSF1RMERTK | |
| SCHEMBL3697573 | 0.91 | BACE1 (0.51) | TTKBACE1PRKDCMERTKAXL | |
| SCHEMBL4766002 | 0.85 | TTK (0.47) | TTKPRKDCCSF1RMERTKAXL | |
| SCHEMBL2954761 | 0.84 | TTK (0.44) | TTKPRKDCCSF1RMERTKAXL | |
| SCHEMBL2950053 | 0.83 | TTK (0.45) | TTKPRKDCCSF1RMERTKAXL | |
| SCHEMBL2950051 | 0.83 | TTK (0.45) | TTKPRKDCCSF1RMERTKAXL | |
| SCHEMBL2950176 | 0.81 | TTK (0.46) | TTKPRKDCCSF1RMERTKAXL | |
| SCHEMBL2953247 | 0.77 | TTK (0.47) | TTKPRKDCCSF1RMERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |