SCHEMBL30383045

SCHEMBL30383045

Nc1ccccc1S(=O)(=O)Nc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)cc1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.52
TERT O14746 1/20 0.52
SNCA P37840 1/20 0.52
CXCL12 P48061 1/20 0.51
MEN1 O00255 1/20 0.51
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
P4HB P07237 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3484356 1.00 MAPT (0.52) MAPTTERTSNCACXCL12MEN1
SCHEMBL3484359 1.00 MAPT (0.52) MAPTTERTSNCACXCL12MEN1
SCHEMBL3484447 0.88 F3 (0.54) MAPTCXCL12MEN1KMT2AP4HB
SCHEMBL3484449 0.88 F3 (0.54) MAPTCXCL12MEN1KMT2AP4HB
SCHEMBL30384281 0.88 F3 (0.54) MAPTCXCL12MEN1KMT2AP4HB
SCHEMBL3484320 0.87 MAPT (0.52) MAPTTERTSNCACXCL12MEN1
SCHEMBL30383490 0.87 MAPT (0.52) MAPTTERTSNCACXCL12MEN1
SCHEMBL3484322 0.87 MAPT (0.52) MAPTTERTSNCACXCL12MEN1
SCHEMBL3484404 0.84 MAPT (0.62) MAPTTERTSNCACXCL12MEN1
SCHEMBL3484400 0.84 MAPT (0.62) MAPTTERTSNCACXCL12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed